GALLERY: St. Louis County’s mass vaccination site opens Wednesday


Photo by Erin Achenbach

Members of the Visiting Nurses Association, National Guard, county employees and volunteers help administer the vaccine at the mass vaccination site in Ferguson Tuesday, Feb. 2, 2021. In addition to the mass vaccination site at the Florissant Valley campus of St. Louis Community College, additional vaccination sites are open in the Mehlville, Affton and Eureka fire protection districts, which began administering vaccines to eligible members of the public who had appointments Thursday, Feb. 4.

St. Louis County’s first mass vaccination site, at the Florissant Valley campus of St. Louis Community College in Ferguson, is expected to open for public vaccinations Wednesday. 

The county conducted a “soft opening” of the mass vaccination site Tuesday, administering the vaccine to eligible county employees ahead of vaccinations for the public the following day.

Health officials stressed that no walk-ups will not be taken at any county vaccine site, and shots will only be given out to those who have been contacted from the county’s preregistration list to make an appointment. See below for how to register.

The St. Louis County Department of Public Health received 3,900 doses of the Pfizer COVID-19 vaccine Tuesday from a local hospital partner. It is estimated that 500 to 1,000 shots can be administered at the Ferguson location per day. 

The county also announced Tuesday that additional vaccination sites would open in South County in the Mehlville and Affton fire districts, with another site in Eureka. Appointments for shots will begin in the three fire districts Thursday, also from the county’s preregistration list. 

The Florissant Valley vaccination site has been set up since Friday and has been vaccinating qualified employees with the county. 

The county will send invitations to currently preregistered individuals to schedule appointments and choose which of the five sites to get a shot. 

Appointments are required, so preregister online at or by emailing The county urges those who need assistance registering online to get help from family members or friends. Those who do not have internet access may call 314-615-2660 to register.

More than 4,800 people have received their first dose of the COVID-19 vaccine through the St. Louis County Department of Public Health as of Monday, and roughly 1,000 of them have received a second dose.

More than 750 of those are first responders, and St. Louis County reached an agreement last week with SSM Health to vaccinate as many as 4,000 additional first responders, most of which are law enforcement. The vaccinations began Monday at St. Louis University Hospital.